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Ligand · 354

354 · N-[(S)-(4-{[(2-amino-4-hydroxyquinazolin-6-yl)(dihydroxy)-lambda~4~-sulfanyl]amino}phenyl)(hydroxy)methyl]-L-glutamic acid

354, N-[(S)-(4-{[(2-amino-4-hydroxyquinazolin-6-yl)(dihydroxy)-lambda~4~-sulfanyl]amino}phenyl)(hydroxy)methyl]-L-glutamic acid (C20 H23 N5 O8 S, 493.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
354
Formula
C20 H23 N5 O8 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

354 in 2 structures; the first of them:

  • 1P4R · Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD · 354 A1801 · binds ASN431, GLN449, SER450, ARG451, ILE452, PHE541, PRO543, PHE544 and 14 more
  • 1P4R · Crystal structure of human atic in complex with folate- based inhibitor BW1540U88UD · 354 A1801 · binds ASN431, GLN449, SER450, ARG451, ILE452, PHE541, PRO543, PHE544 and 14 more

Residues it binds most

ASN 4, PHE 4, SER 4, ASP 4, ALA 4, GLY 4, ARG 4, GLN 4, ILE 4, LYS 4 (residue and the binding sites it lines).

Found with

  • AMZ · Aminoimidazole 4-carboxamide ribonucleotide
  • XMP · Xanthosine-5'-monophosphate
  • K · Potassium ion

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