MolNFT v1 · #128402 · protein

ABL2 SH3 PTYR116/161

5NP5 · Abelson tyrosine-protein kinase 2: “ABL2 SH3 PTYR116/161”. X-ray diffraction, 1 ligand (SO4). MolNFT v1 #128402 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5NP5
Type: protein
Length: 118 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Abelson tyrosine-protein kinase 2
EC: 2.7.10.2
UniProt: P42684
Ligands: SO4

Structure

x-ray diffraction · 2 distinct chains · 5% helix, 47% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Abelson tyrosine-protein kinase 2 (EC 2.7.10.2)	protein	61	5% helix, 48% strand	P42684
B	Abelson tyrosine-protein kinase 2 (EC 2.7.10.2)	protein	57	5% helix, 46% strand	P42684

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 612 Å² buried · 5 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (phosphorylation).

Compared structures

5NP5 · Abl2 SH3 pTyr116/161 · the same entry in another collection · chain A against A, TM-score 1.00
P42684 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase ABL2 (P42684) · a predicted model of the same protein · chain B against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P42684
Elsewhere: RCSB PDB 5NP5 · PDBe 5NP5 · UniProt P42684

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.