MolNFT v1 · #128388 · protein
Structure of cyclophilin a in complex with 3-methylpyridin-2-amine
5NOR · Peptidyl-prolyl cis-trans isomerase a: “Structure of cyclophilin a in complex with 3-methylpyridin-2-amine”. X-ray diffraction, 1 ligand (93Q), 1 pocket (best druggability 0.32). MolNFT v1 #128388 on GenesisL1: 3D structure, binding…
- PDB
- 5NOR
- Type
- protein
- Length
- 165 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Peptidyl-prolyl cis-trans isomerase a
- EC
- 5.2.1.8
- UniProt
- P62937
- Ligands
- 93Q
- Pockets
- 1 · best druggability 0.32
Structure
x-ray diffraction · 1 distinct chain · 14% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Peptidyl-prolyl cis-trans isomerase a (EC 5.2.1.8) | protein | 165 | 14% helix, 33% strand | P62937 |
Ligands and binding sites
- 93Q · 3-methylpyridin-2-amine · ligand · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.32 | 0.78 | 16 | 93Q |
Compared structures
- 5NOR · Structure of cyclophilin A in complex with 3-methylpyridin-2-amine · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62937
- Elsewhere: RCSB PDB 5NOR · PDBe 5NOR · UniProt P62937
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.