MolNFT v1 · #128329 · protein
Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with N-acetyl-cysteine
5NN4: “Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with N-acetyl-cysteine”. X-ray diffraction, 6 ligands (NAG, FUC, BMA). MolNFT v1 #128329 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5NN4
- Type
- protein
- Length
- 849 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P10253
- Ligands
- NAG, FUC, BMA, MAN, SO4, CL
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 849 | — | P10253 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 10 copies · chains A
- FUC · alpha-L-fucopyranose · sugar · 2 copies · chains A
- BMA · beta-D-mannopyranose · sugar · 2 copies
- MAN · alpha-D-mannopyranose · sugar
- SO4 · Sulfate ion · ion · 4 copies · chains A
- CL · Chloride ion · ion · 2 copies · chains A
- EDO · 1,2-ethanediol · additive · 18 copies · chains A
- GOL · Glycerol · additive · 2 copies · chains A
- PGE · Triethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5NN4 · Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
- P10253 · AlphaFold monomer V2.0 prediction for lysosomal alpha-glucosidase (P10253) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10253
- Elsewhere: RCSB PDB 5NN4 · PDBe 5NN4 · UniProt P10253
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