MolNFT v1 · #128326 · protein

The structure of the polo-box domain (pbd) of polo-like kinase 1 (PLK1)

5NN1 · SERINE/THREONINE-protein kinase PLK1: “The structure of the polo-box domain (pbd) of polo-like kinase 1 (PLK1)”. X-ray diffraction, 1 pocket (best druggability 0.43). MolNFT v1 #128326 on GenesisL1: 3D structure, binding sites and…

PDB: 5NN1
Type: protein
Length: 215 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: SERINE/THREONINE-protein kinase PLK1
EC: 2.7.11.21
UniProt: P53350
Pockets: 1 · best druggability 0.43

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SERINE/THREONINE-protein kinase PLK1 (EC 2.7.11.21)	protein	215	32% helix, 30% strand	P53350

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	107	0.43	0.77	20	empty

Compared structures

5NN1 · The structure of the polo-box domain (PBD) of polo-like kinase 1 (Plk1) · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P53350
Elsewhere: RCSB PDB 5NN1 · PDBe 5NN1 · UniProt P53350

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.