MolNFT v1 · #128232 · protein
Crystal structure of ephrin A2 (EPHA2) receptor protein kinase with compound 4A
5NKB: “Crystal structure of ephrin A2 (EPHA2) receptor protein kinase with compound 4A”. X-ray diffraction, 1 ligand (8ZT). MolNFT v1 #128232 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5NKB
- Type
- protein
- Length
- 285 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P29317
- Ligands
- 8ZT
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 285 | — | P29317 |
Ligands and binding sites
- 8ZT · ~{N}-(2-chloranyl-6-methyl-phenyl)-2-[(3,5-dimorpholin-4-ylphenyl)amino]-1,3-thiazole-5-carboxamide · ligand · chains A
- EDO · 1,2-ethanediol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5NKB · Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 4a · the same entry in another collection · chain A against A, TM-score 1.00
- P29317 · AlphaFold monomer V2.0 prediction for ephrin type-a receptor 2 (P29317) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P29317
- Elsewhere: RCSB PDB 5NKB · PDBe 5NKB · UniProt P29317
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.