MolNFT v1 · #128097 · protein
Crystal structure of USP7 in complex with the covalent inhibitor, FT827
5NGF: “Crystal structure of USP7 in complex with the covalent inhibitor, FT827”. X-ray diffraction, 1 ligand (8WN). MolNFT v1 #128097 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5NGF
- Type
- protein
- Length
- 664 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q93009
- Ligands
- 8WN
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 332 | — | Q93009 |
Ligands and binding sites
- 8WN · ~{N}-[2-[4-[4-[(1-methyl-4-oxidanylidene-pyrazolo[3,4-d]pyrimidin-5-yl)methyl]-4-oxidanyl-piperidin-1-yl]carbonylphenyl]phenyl]ethanesulfonamide · ligand · 2 copies · chains A, B
- EDO · 1,2-ethanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5NGF · Crystal structure of USP7 in complex with the covalent inhibitor, FT827 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q93009
- Elsewhere: RCSB PDB 5NGF · PDBe 5NGF · UniProt Q93009
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