MolNFT v1 · #127992 · protein

MPI3KD in complex with INH1

5NCZ: “MPI3KD in complex with INH1”. X-ray diffraction, 1 ligand (8TN). MolNFT v1 #127992 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5NCZ
Type: protein
Length: 827 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: O35904
Ligands: 8TN

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	827	—	O35904

Ligands and binding sites

8TN · 4-azanyl-6-[[(1~{S})-1-[6-[3-[(dimethylamino) methyl]phenyl]-3-methyl-5-oxidanylidene-[1, 3]thiazolo[3,2-a]pyridin-7-yl]ethyl]amino]pyrimidine-5-carbonitrile · ligand · chains A
EDO · 1,2-ethanediol · additive · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5NCZ · mPI3Kd IN COMPLEX WITH inh1 · the same entry in another collection · chain A against A, TM-score 1.00
O35904 · AlphaFold monomer V2.0 prediction for phosphatidylinositol 4,5-bisphosphate 3-kinase… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O35904
Elsewhere: RCSB PDB 5NCZ · PDBe 5NCZ · UniProt O35904

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