MolNFT v1 · #127235 · protein

Glycoside hydrolase BT_0986

5MQM · Glycosyl hydrolases family 2, sugar binding domain: “Glycoside hydrolase BT_0986”. X-ray diffraction, 2 ligands (RPQ, CA), 13 pockets (best druggability 0.80). MolNFT v1 #127235 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 5MQM
Type: protein
Length: 1,038 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glycosyl hydrolases family 2, sugar binding domain
UniProt: A0A0P0FM19
Ligands: RPQ, CA
Pockets: 13 · best druggability 0.80

Structure

x-ray diffraction · 1 distinct chain · 24% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glycosyl hydrolases family 2, sugar binding domain	protein	1038	24% helix, 32% strand	A0A0P0FM19

Ligands and binding sites

RPQ · D-rhamnopyranose tetrazole · ligand · chains A
CA · Calcium ion · metal · 3 copies · chains A
PG4 · Tetraethylene glycol · additive · 2 copies · chains A
PGE · Triethylene glycol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

13 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	633	0.80	0.85	101	empty
2	271	0.60	0.79	41	CA, RPQ, PG4
3	111	0.60	0.86	22	empty
4	312	0.58	0.77	38	empty
5	225	0.52	0.76	42	empty

Compared structures

5MQM · Glycoside hydrolase BT_0986 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0P0FM19
Elsewhere: RCSB PDB 5MQM · PDBe 5MQM · UniProt A0A0P0FM19

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