MolNFT v1 · #127063 · protein
Bromodomain of human GCN5 with 4-bromo-2-methyl-5-(((3R,5R)-1-methyl- 5-phenylpiperidin-3-YL)AMINO)PYRIDAZIN-3(2H)-one
5MLJ: “Bromodomain of human GCN5 with 4-bromo-2-methyl-5-(((3R,5R)-1-methyl…”. X-ray diffraction, 1 ligand (9ST). MolNFT v1 #127063 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5MLJ
- Type
- protein
- Length
- 213 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q92830
- Ligands
- 9ST
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 109 | — | Q92830 |
| B | — | protein | 104 | — | Q92830 |
Ligands and binding sites
- 9ST · 4-bromo-2-methyl-5-[[(3~{R},5~{R})-1-methyl-5-phenyl-piperidin-3-yl]amino]pyridazin-3-one · ligand · 2 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5MLJ · Bromodomain of Human GCN5 with 4-bromo-2-methyl-5-(((3R,5R)-1-methyl-5-phenylpiperidin-3-y… · the same entry in another collection · chain A against A, TM-score 1.00
- Q92830 · AlphaFold monomer V2.0 prediction for histone acetyltransferase KAT2A (Q92830) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q92830
- Elsewhere: RCSB PDB 5MLJ · PDBe 5MLJ · UniProt Q92830
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