MolNFT v1 · #126386 · protein

Structure of a spumaretrovirus gag central domain reveals an ancient retroviral capsid

5M1H · Gag protein: “Structure of a spumaretrovirus gag central domain reveals an ancient retroviral capsid”. Solution nmr, 2 pockets (best druggability 0.30). MolNFT v1 #126386 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5M1H
Type: protein
Length: 180 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Gag protein
UniProt: P14349
Pockets: 2 · best druggability 0.30

Structure

solution nmr · 1 distinct chain · 62% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Gag protein	protein	180	62% helix, 0% strand	P14349

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.30	0.76	16	empty
2	56	0.26	0.72	10	empty

Compared structures

5M1H · Structure of a Spumaretrovirus Gag central domain reveals an ancient retroviral capsid · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P14349
Elsewhere: RCSB PDB 5M1H · PDBe 5M1H · UniProt P14349

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