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MolNFT v1 · #125754 · protein

Structure of a peptide-substrate bound to pkciota core kinase domain

5LIH: “Structure of a peptide-substrate bound to pkciota core kinase domain”. X-ray diffraction, 4 ligands (AF3, ADP, MN). MolNFT v1 #125754 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5LIH
Type
protein
Length
669 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P41743
Ligands
AF3, ADP, MN, SCN

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein326—P41743
B—protein320—P41743
F—protein13——
G—protein10——

Ligands and binding sites

  • AF3 · Aluminum fluoride · ligand · 4 copies · chains A, F, B, G
  • ADP · Adenosine-5'-diphosphate · ligand · 2 copies · chains A, F, B, G
  • MN · Manganese (II) ion · metal · 5 copies · chains A, B, G
  • SCN · Thiocyanate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 5LIH · Structure of a peptide-substrate bound to PKCiota core kinase domain · the same entry in another collection · chain A against A, TM-score 1.00
  • P41743 · AlphaFold monomer V2.0 prediction for protein kinase C iota type (P41743) · a predicted model of the same protein · chain B against A, TM-score 0.98

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