MolNFT v1 · #125672 · protein
Solution NMR structure of tryptophan to alanine mutant of arkadia ring domain.
5LG0 · E3 ubiquitin-protein ligase arkadia: “Solution NMR structure of tryptophan to alanine mutant of arkadia ring domain.”. Solution nmr, 1 ligand (ZN), 1 pocket (best druggability 0.31). MolNFT v1 #125672 on GenesisL1: 3D structure…
- PDB
- 5LG0
- Type
- protein
- Length
- 69 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- E3 ubiquitin-protein ligase arkadia
- EC
- 6.3.2.-
- UniProt
- Q6ZNA4
- Ligands
- ZN
- Pockets
- 1 · best druggability 0.31
Structure
solution nmr · 1 distinct chain · 14% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase arkadia (EC 6.3.2.-) | protein | 69 | 14% helix, 20% strand | Q6ZNA4 |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 64 | 0.31 | 0.75 | 15 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 5LG0 · Solution NMR structure of Tryptophan to Alanine mutant of Arkadia RING domain. · the same entry in another collection · chain A against A, TM-score 1.00
- Q6ZNA4 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase arkadia (Q6ZNA4) · a predicted model of the same protein · chain A against A, TM-score 0.69
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6ZNA4
- Elsewhere: RCSB PDB 5LG0 · PDBe 5LG0 · UniProt Q6ZNA4
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