UniProt Q6ZNA4
E3 ubiquitin-protein ligase Arkadia (Q6ZNA4)
E3 ubiquitin-protein ligase Arkadia (UniProt Q6ZNA4), EC 2.3.2.27, 6.3.2.-: 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 4 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q6ZNA4
- Protein
- E3 ubiquitin-protein ligase Arkadia
- EC
- 2.3.2.27, 6.3.2.-
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 4 · 0 records with a druggable one
Structures
9 records of Q6ZNA4 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2KIZ | Solution structure of Arkadia RING-H2 finger domain | solution nmr | A | — | — |
| 2KIZ | Solution structure of arkadia ring-H2 finger domain | solution nmr | A | — | — |
| 5LG0 | Solution NMR structure of Tryptophan to Alanine mutant of Arkadia RING domain. | solution nmr | A | ZN | 1 (best 0.31) |
| 5LG0 | Solution NMR structure of tryptophan to alanine mutant of arkadia ring domain. | solution nmr | A | ZN | — |
| 5LG7 | Solution NMR structure of Tryptophan to Arginine mutant of Arkadia RING domain | solution nmr | A | ZN | 1 (best 0.37) |
| 5LG7 | Solution NMR structure of tryptophan to arginine mutant of arkadia ring domain | solution nmr | A | ZN | — |
| 7P2K | Solution NMR Structure of Arginine to Cysteine mutant of Arkadia RING domain. | solution nmr | A | ZN | 1 (best 0.33) |
| 7P2K | Solution NMR structure of arginine to cysteine mutant of arkadia ring domain. | solution nmr | A | ZN | — |
| Q6ZNA4 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase arkadia (Q6ZNA4) | predicted | A | — | 1 (best 0.36) |
Ligands
- ZN · Zinc ion · in 6 records
Experiment against prediction
- 5LG0 chain A against the predicted model Q6ZNA4: TM-score 0.69, RMSD 2.33 Å
- 5LG0 chain A against the predicted model Q6ZNA4: TM-score 0.69, RMSD 2.33 Å
- 5LG7 chain A against the predicted model Q6ZNA4: TM-score 0.62, RMSD 2.96 Å
- 5LG7 chain A against the predicted model Q6ZNA4: TM-score 0.62, RMSD 2.96 Å
- 7P2K chain A against the predicted model Q6ZNA4: TM-score 0.60, RMSD 2.55 Å
- 7P2K chain A against the predicted model Q6ZNA4: TM-score 0.60, RMSD 2.55 Å
- 2KIZ chain A against the predicted model Q6ZNA4: TM-score 0.57, RMSD 2.79 Å
- 2KIZ chain A against the predicted model Q6ZNA4: TM-score 0.57, RMSD 2.79 Å
Elsewhere
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