MolNFT v1 · #125436 · protein

Apo-structure of humanised rada-mutant HUMRADA4

5L8V · DNA repair and recombination protein rada: “Apo-structure of humanised rada-mutant HUMRADA4”. X-ray diffraction, 1 ligand (PO4), 2 pockets (best druggability 0.38). MolNFT v1 #125436 on GenesisL1: 3D structure, binding sites and…

PDB: 5L8V
Type: protein
Length: 223 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA repair and recombination protein rada
UniProt: O74036
Ligands: PO4
Pockets: 2 · best druggability 0.38

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA repair and recombination protein rada	protein	223	37% helix, 25% strand	O74036

Ligands and binding sites

PO4 · Phosphate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	102	0.38	0.76	20	PO4
2	64	0.32	0.75	17	empty

Compared structures

5L8V · Apo-structure of humanised RadA-mutant humRadA4 · the same entry in another collection · chain A against A, TM-score 1.00
O74036 · AlphaFold monomer V2.0 prediction for DNA repair and recombination protein rada (O74036) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O74036
Elsewhere: RCSB PDB 5L8V · PDBe 5L8V · UniProt O74036

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