Fdhc with bound products: coenzyme a and dtdp-3-amino-3,6-dideoxy-D- glucose

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 28% strand (DSSP).

Ligands and binding sites

• QUH · [[(2~{R},3~{S},5~{R})-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{S}, 5~{S},6~{R})-6-methyl-3,5-bis(oxidanyl)-4-[[(3~{R})-3-oxidanylbutanoyl]amino]oxan-2-yl] hydrogen phosphate · ligand · chains A
• COA · Coenzyme A · ligand · chains A
• MG · Magnesium ion · metal · chains A
• EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Compared structures

• 5KTD · FdhC with bound products: Coenzyme A and dTDP-3-amino-3,6-dideoxy-d-glucose · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt V5RDR9
• Elsewhere: RCSB PDB 5KTD · PDBe 5KTD · UniProt V5RDR9