MolNFT v1 · #124818 · protein
Solution structure of antibiotic-resistance factor ANT(2'')-ia reveals substrate-regulated conformation dynamics
5KQJ · 2''-aminoglycoside nucleotidyltransferase: “Solution structure of antibiotic-resistance factor ANT(2'')-ia reveals substrate-regulated conformation…”. Solution nmr, 1 pocket (best druggability 0.60). MolNFT v1 #124818 on GenesisL1…
- PDB
- 5KQJ
- Type
- protein
- Length
- 185 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 2''-aminoglycoside nucleotidyltransferase
- EC
- 2.7.7.46
- UniProt
- P0AE05
- Pockets
- 1 · best druggability 0.60
Structure
solution nmr · 1 distinct chain · 50% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 2''-aminoglycoside nucleotidyltransferase (EC 2.7.7.46) | protein | 185 | 50% helix, 23% strand | P0AE05 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 291 | 0.60 | 0.79 | 35 | empty |
Compared structures
- 5KQJ · Solution Structure of Antibiotic-Resistance Factor ANT(2'')-Ia Reveals… · the same entry in another collection · chain A against A, TM-score 1.00
- P0AE05 · AlphaFold monomer V2.0 prediction for 2''-aminoglycoside nucleotidyltransferase (P0AE05) · a predicted model of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0AE05
- Elsewhere: RCSB PDB 5KQJ · PDBe 5KQJ · UniProt P0AE05
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