UniProt P0AE05
2''-aminoglycoside nucleotidyltransferase (P0AE05)
2''-aminoglycoside nucleotidyltransferase (UniProt P0AE05), EC 2.7.7.46: 5 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction…
- UniProt
- P0AE05
- Protein
- 2''-aminoglycoside nucleotidyltransferase
- EC
- 2.7.7.46
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 1 · 1 record with a druggable one
Structures
6 records of P0AE05 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4WQK | Crystal structure of aminoglycoside nucleotidylyltransferase ANT(2)-Ia | x-ray diffraction | A | MG, CL | 1 (best 0.64) |
| 4WQK | Crystal structure of aminoglycoside nucleotidylyltransferase ANT(2")- ia, apo form | x-ray diffraction | A | — | — |
| 4WQL | Crystal structure of aminoglycoside nucleotidylyltransferase ANT(2")- ia, kanamycin-bound | x-ray diffraction | A | — | — |
| 5KQJ | Solution Structure of Antibiotic-Resistance Factor ANT(2'')-Ia Reveals Substrate-Regulated… | solution nmr | A | — | — |
| 5KQJ | Solution structure of antibiotic-resistance factor ANT(2'')-ia reveals substrate-regulated… | solution nmr | A | — | — |
| P0AE05 | AlphaFold monomer V2.0 prediction for 2''-aminoglycoside nucleotidyltransferase (P0AE05) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4WQK chain A against the predicted model P0AE05: TM-score 0.99, RMSD 0.59 Å
- 4WQK chain A against the predicted model P0AE05: TM-score 0.99, RMSD 0.59 Å
- 4WQL chain A against the predicted model P0AE05: TM-score 0.99, RMSD 0.60 Å
- 5KQJ chain A against the predicted model P0AE05: TM-score 0.93, RMSD 0.96 Å
- 5KQJ chain A against the predicted model P0AE05: TM-score 0.93, RMSD 0.96 Å
Elsewhere
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