MolNFT v1 · #124767 · protein
Structure of rifampicin monooxygenase
5KOW · Pentachlorophenol 4-monooxygenase: “Structure of rifampicin monooxygenase”. X-ray diffraction, 1 ligand (FAD), 4 pockets (best druggability 0.81). MolNFT v1 #124767 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5KOW
- Type
- protein
- Length
- 474 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pentachlorophenol 4-monooxygenase
- EC
- 1.14.13.50
- UniProt
- A0A0H5NE66
- Ligands
- FAD
- Pockets
- 4 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pentachlorophenol 4-monooxygenase (EC 1.14.13.50) | protein | 474 | 33% helix, 23% strand | A0A0H5NE66 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1003 | 0.81 | 0.82 | 94 | FAD |
| 2 | 125 | 0.56 | 0.83 | 26 | empty |
| 3 | 99 | 0.38 | 0.76 | 19 | empty |
| 4 | 81 | 0.32 | 0.74 | 15 | empty |
Compared structures
- 5KOW · Structure of rifampicin monooxygenase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0H5NE66
- Elsewhere: RCSB PDB 5KOW · PDBe 5KOW · UniProt A0A0H5NE66
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