MolNFT v1 · #124720 · protein

Crystal structure of the wild-type SAM domain of human tankyrase-1

5KNI: “Crystal structure of the wild-type SAM domain of human tankyrase-1”. X-ray diffraction. MolNFT v1 #124720 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5KNI
Type: protein
Length: 430 residues
Chains: 7
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tankyrase-1
EC: 2.4.2.30
UniProt: O95271

Structure

x-ray diffraction · 6 distinct chains · 67% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tankyrase-1 (EC 2.4.2.30)	protein	58	67% helix, 0% strand	O95271
B	Tankyrase-1 (EC 2.4.2.30)	protein	60	67% helix, 0% strand	O95271
C	Tankyrase-1 (EC 2.4.2.30)	protein	65	66% helix, 0% strand	O95271
D, F	Tankyrase-1 (EC 2.4.2.30)	protein	61	67% helix, 0% strand	O95271
E	Tankyrase-1 (EC 2.4.2.30)	protein	62	69% helix, 0% strand	O95271
G	Tankyrase-1 (EC 2.4.2.30)	protein	63	68% helix, 0% strand	O95271

Interfaces

6 interfaces between chains.

D–E · 423 Å² buried · 5 hydrogen bonds · protein-protein
E–F · 413 Å² buried · 7 hydrogen bonds · protein-protein
B–C · 404 Å² buried · 7 hydrogen bonds · protein-protein
C–D · 401 Å² buried · 6 hydrogen bonds · protein-protein
A–B · 399 Å² buried · 3 hydrogen bonds · protein-protein

Compared structures

5KNI · Crystal Structure of the wild-type SAM domain of human Tankyrase-1 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O95271
Elsewhere: RCSB PDB 5KNI · PDBe 5KNI · UniProt O95271

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