Crystal structure of a domain-swapped dimer of yeast iso-1-cytochrome C with CYMAL5

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 2% strand (DSSP).

Ligands and binding sites

• HEC · Heme C · ligand · chains A
• CM5 · 5-cyclohexyl-1-pentyl-beta-D-maltoside · ligand · chains A
• SO4 · Sulfate ion · ion · 2 copies · chains A
• CL · Chloride ion · ion · chains A
• GOL · Glycerol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 2 cofactor (heme c attachment).

Compared structures

• 5KKE · Crystal Structure of a Domain-swapped Dimer of Yeast Iso-1-cytochrome c with CYMAL5 · the same entry in another collection · chain A against A, TM-score 1.00
• P00044 · AlphaFold monomer V2.0 prediction for cytochrome C isoform 1 (P00044) · a predicted model of the same protein · chain A against A, TM-score 0.71

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P00044
• Elsewhere: RCSB PDB 5KKE · PDBe 5KKE · UniProt P00044