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Ligand · CM5

CM5 · 5-cyclohexyl-1-pentyl-beta-D-maltoside

CM5, 5-cyclohexyl-1-pentyl-beta-D-maltoside (C23 H42 O11, 494.6 g/mol), in the MolNFT structures on GenesisL1: bound in 11 records (10 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
CM5
Formula
C23 H42 O11
Class
ligand
Structures
11
PDB entries
10

Binding sites

CM5 in 11 structures; the first of them:

  • 5EM4 · Structure of CYP2B4 F244W in a ligand free conformation · CM5 A502 · binds SER176, LYS186, PHE188, VAL194, PHE195, LEU198, LEU199, PHE202 and 2 more
  • 6CXH · Crystal structure of particulate methane monooxygenase from Methylomicrobium alcaliphilum… · CM5 A502 · binds MET203, VAL204, CYS207, ARG208, ARG19, TYR23
  • 5KKE · Crystal structure of a domain-swapped dimer of yeast iso-1-cytochrome C with CYMAL5 · CM5 A204 · binds SER40, GLY41, TYR48, ASN52, LYS55, VAL57, TYR67, LYS73 and 1 more
  • 5UAP · Crystal structure of CYP2B6 (Y226H/K262R) in complex with bornyl bromide · CM5 A502 · binds PHE220, PHE223
  • 5UDA · Crystal structure of CYP2B6 (Y226H/K262R) in complex with a monoterpene bornane · CM5 A503 · binds PHE220, PHE223
  • 5UEC · Crystal structure of CYP2B6 (Y226H/K262R) in complex with myrtenyl bromide. · CM5 A502 · binds CYS180, PHE188, GLU194, MET198, PHE202, ILE241, TYR244, HIS247 and 1 more
  • 5UFG · Crystal structure of CYP2B6 (Y226H/K262R/I114V) in complex with myrtenyl bromide · CM5 A502 · binds PHE220, PHE223
  • 5WBG · Crystal structure of human cytochrome P450 2B6 (Y226H/K262R) in complex with an analog of… · CM5 B503 · binds LEU39, LEU40, PHE220, GLY222, PHE223
  • 6BWW · Crystal structure of an acetate and cymal-5 bound cytochrome P450 2B4 F429H mutant · CM5 A502 · binds SER176, CYS180, LYS186, PHE188, VAL194, PHE195, LEU198, PHE202 and 4 more
  • 6CXH · Crystal structure of particulate methane monooxygenase from methylomicrobium alcaliphilum… · CM5 A502 · binds MET203, VAL204, CYS207, ARG208, ARG19, TYR23
  • 6VLT · Crystal structure of human P450 2C9*2 genetic variant in complex with losartan · CM5 E501 · binds PRO227, THR229, TYR225, PHE226

Residues it binds most

PHE 28, LEU 18, TYR 17, MET 18, GLY 15, VAL 15, LYS 12, ARG 11, PRO 11, ASP 11 (residue and the binding sites it lines).

Found with

  • HEM · Protoporphyrin IX containing Fe
  • 85D · (1S,5R)-2-(bromomethyl)-6,6-dimethylbicyclo[3.1.1]hept-2-ene
  • CU · Copper (II) ion
  • SO4 · Sulfate ion
  • GOL · Glycerol
  • 82S · (1R,2R,4R)-2-bromo-1,7,7-trimethylbicyclo[2.2.1]heptane
  • 9ZJ · (2R,4S)-6-chloro-4-(cyclopropylethynyl)-2-methyl-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazine
  • CAE · Camphane
  • HEC · Heme C
  • LSN · [2-butyl-5-chloranyl-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
  • ZAZ · 5-cyclohexylpentan-1-ol
  • CL · Chloride ion

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