MolNFT v1 · #124539 · protein + RNA
Human argonaute-2 bound to a guide RNA with a nucleobase modification at position 1
5KI6: “Human argonaute-2 bound to a guide RNA with a nucleobase modification at position 1”. X-ray diffraction, 1 ligand (IPH). MolNFT v1 #124539 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5KI6
- Type
- protein + RNA
- Length
- 808 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9UKV8
- Ligands
- IPH
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 798 | — | Q9UKV8 |
| B | — | rna | 10 | — | — |
Ligands and binding sites
- IPH · Phenol · ligand · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5KI6 · Human Argonaute-2 bound to a guide RNA with a nucleobase modification at position 1 · the same entry in another collection · chain A against A, TM-score 1.00
- Q9UKV8 · AlphaFold monomer V2.0 prediction for protein argonaute-2 (Q9UKV8) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UKV8
- Elsewhere: RCSB PDB 5KI6 · PDBe 5KI6 · UniProt Q9UKV8
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