MolNFT v1 · #124141 · protein
Crystal structure of prefusion-stabilized rsv F single-chain 9-10 ds- CAV1 A149C-Y458C variant.
5K6H · Fusion glycoprotein F0: “Crystal structure of prefusion-stabilized rsv F single-chain 9-10 ds- CAV1 A149C-Y458C variant.”. X-ray diffraction, 5 pockets (best druggability 0.57). MolNFT v1 #124141 on GenesisL1: 3D structure, binding…
- PDB
- 5K6H
- Type
- protein
- Length
- 445 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fusion glycoprotein F0
- UniProt
- P03420
- Pockets
- 5 · best druggability 0.57
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| F | Fusion glycoprotein F0 | protein | 445 | 32% helix, 34% strand | P03420 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 151 | 0.57 | 0.82 | 22 | empty |
| 2 | 160 | 0.48 | 0.77 | 19 | empty |
| 3 | 69 | 0.32 | 0.75 | 15 | empty |
| 4 | 73 | 0.30 | 0.74 | 15 | empty |
| 5 | 60 | 0.30 | 0.75 | 16 | empty |
Modifications
Observed in the structure: 8 disulfide (disulfide).
Compared structures
- 5K6H · Crystal structure of prefusion-stabilized RSV F single-chain 9-10 DS-Cav1 A149C-Y458C… · the same entry in another collection · chain F against F, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03420
- Elsewhere: RCSB PDB 5K6H · PDBe 5K6H · UniProt P03420
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.