UniProt P03420
Fusion glycoprotein F0,Fibritin (P03420)
Fusion glycoprotein F0,Fibritin (UniProt P03420): 69 experimental structures on GenesisL1, 11 ligands bound, 49 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P03420
- Protein
- Fusion glycoprotein F0,Fibritin
- Experimental structures
- 69
- Predicted models
- 0
- Ligands
- 11
- Pockets
- 49 · 5 records with a druggable one
Structures
69 records of P03420 in the MolNFT archive: 69 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3IXT | Crystal Structure of Motavizumab Fab Bound to Peptide Epitope | x-ray diffraction | P, C | — | — |
| 3IXT | Crystal structure of motavizumab Fab bound to peptide epitope | x-ray diffraction | P, C | — | — |
| 3KPE | Solution structure of the respiratory syncytial virus (RSV)six-helix bundle complexed with… | x-ray diffraction | A, B | — | — |
| 3KPE | Solution structure of the respiratory syncytial virus (RSV)SIX-helix bundle complexed with… | x-ray diffraction | A, B | — | — |
| 3O41 | Crystal Structure of 101F Fab Bound to 15-mer Peptide Epitope | x-ray diffraction | P, C | — | — |
| 3O41 | Crystal structure of 101F Fab bound to 15-mer peptide epitope | x-ray diffraction | P, C | — | — |
| 3O45 | Crystal Structure of 101F Fab Bound to 17-mer Peptide Epitope | x-ray diffraction | P, C | — | — |
| 3O45 | Crystal structure of 101F Fab bound to 17-mer peptide epitope | x-ray diffraction | P, C | — | — |
| 3RKI | Structural basis for immunization with post-fusion RSV F to elicit high neutralizing antibody titers | x-ray diffraction | A, B, C | — | — |
| 3RKI | Structural basis for immunization with post-fusion rsv F to elicit high neutralizing antibody titers | x-ray diffraction | A, B, C | — | — |
| 4JHW | Crystal Structure of Respiratory Syncytial Virus Fusion Glycoprotein Stabilized in the Prefusion… | x-ray diffraction | F | — | — |
| 4JHW | Crystal structure of respiratory syncytial virus fusion glycoprotein stabilized in the prefusion… | x-ray diffraction | F | — | — |
| 4MMQ | Crystal Structure of Prefusion-stabilized RSV F Variant DS | x-ray diffraction | A, B | — | — |
| 4MMQ | Crystal structure of prefusion-stabilized rsv F variant ds | x-ray diffraction | A, B | — | — |
| 4MMR | Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 9.5 | x-ray diffraction | A, B | — | — |
| 4MMR | Crystal structure of prefusion-stabilized rsv F variant CAV1 at pH 9.5 | x-ray diffraction | A, B | — | — |
| 4MMS | Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 5.5 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4MMS | Crystal structure of prefusion-stabilized rsv F variant CAV1 at pH 5.5 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4MMT | Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1 at pH 9.5 | x-ray diffraction | A, B | — | — |
| 4MMT | Crystal structure of prefusion-stabilized rsv F variant ds-CAV1 at pH 9.5 | x-ray diffraction | A, B | — | — |
| 4MMU | Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1 at pH 5.5 | x-ray diffraction | A, B | — | — |
| 4MMU | Crystal structure of prefusion-stabilized rsv F variant ds-CAV1 at pH 5.5 | x-ray diffraction | A, B | — | — |
| 4MMV | Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1-TriC at pH 9.5 | x-ray diffraction | A, B | — | — |
| 4MMV | Crystal structure of prefusion-stabilized rsv F variant ds-CAV1-tric at pH 9.5 | x-ray diffraction | A, B | — | — |
| 4ZYP | Crystal Structure of Motavizumab and Quaternary-Specific RSV-Neutralizing Human Antibody AM14 in… | x-ray diffraction | A, B, C | — | — |
| 4ZYP | Crystal structure of motavizumab and quaternary-specific rsv- neutralizing human antibody AM14 in… | x-ray diffraction | A, B, C | — | — |
| 5C69 | Crystal structure of prefusion-stabilized rsv F variant pr-dm | x-ray diffraction | A | — | — |
| 5C6B | Crystal structure of prefusion-stabilized rsv F variant sc-tm | x-ray diffraction | F | — | — |
| 5EA3 | Crystal Structure of Inhibitor JNJ-2408068 in Complex with Prefusion RSV F Glycoprotein | x-ray diffraction | F | SO4, 5NK | 3 (best 0.29) |
| 5EA3 | Crystal structure of inhibitor jnj-2408068 in complex with prefusion rsv F glycoprotein | x-ray diffraction | F | — | — |
| 5EA4 | Crystal Structure of Inhibitor JNJ-49153390 in Complex with Prefusion RSV F Glycoprotein | x-ray diffraction | F | SO4, 5NM | — |
| 5EA4 | Crystal structure of inhibitor jnj-49153390 in complex with prefusion rsv F glycoprotein | x-ray diffraction | F | — | — |
| 5EA5 | Crystal Structure of Inhibitor TMC-353121 in Complex with Prefusion RSV F Glycoprotein | x-ray diffraction | F | TM3, SO4 | — |
| 5EA5 | Crystal structure of inhibitor tmc-353121 in complex with prefusion rsv F glycoprotein | x-ray diffraction | F | — | — |
| 5EA6 | Crystal Structure of Inhibitor BTA-9881 in Complex with Prefusion RSV F Glycoprotein | x-ray diffraction | F | SO4, 5NP | 2 (best 0.28) |
| 5EA6 | Crystal structure of inhibitor bta-9881 in complex with prefusion rsv F glycoprotein | x-ray diffraction | F | — | — |
| 5EA7 | Crystal structure of inhibitor bms-433771 in complex with prefusion rsv F glycoprotein | x-ray diffraction | F | — | — |
| 5EA8 | Crystal Structure of Prefusion RSV F Glycoprotein Fusion Inhibitor Resistance Mutant D489Y | x-ray diffraction | F | SO4 | — |
| 5EA8 | Crystal structure of prefusion rsv F glycoprotein fusion inhibitor resistance mutant D489Y | x-ray diffraction | F | — | — |
| 5J3D | Crystal structure of human Fab 14N4 in complex with post-fusion RSV F | x-ray diffraction | E, F, G, I, J, K | — | — |
| 5J3D | Crystal structure of human Fab 14N4 in complex with post-fusion rsv F | x-ray diffraction | E, F, G, I, J, K | — | — |
| 5K6B | Crystal structure of prefusion-stabilized rsv F single-chain 9 ds-CAV1 variant. | x-ray diffraction | F | NAG, SO4 | — |
| 5K6C | Crystal structure of prefusion-stabilized RSV F single-chain 9-10 DS-Cav1 variant. | x-ray diffraction | F | SO4 | — |
| 5K6C | Crystal structure of prefusion-stabilized rsv F single-chain 9-10 ds- CAV1 variant. | x-ray diffraction | F | SO4 | — |
| 5K6F | Crystal structure of prefusion-stabilized RSV F single-chain 9-19 DS-Cav1 variant. | x-ray diffraction | F | — | — |
| 5K6F | Crystal structure of prefusion-stabilized rsv F single-chain 9-19 ds- CAV1 variant. | x-ray diffraction | F | — | — |
| 5K6G | Crystal structure of prefusion-stabilized RSV F single-chain 9-24 DS-Cav1 variant. | x-ray diffraction | F | — | 2 (best 0.43) |
| 5K6G | Crystal structure of prefusion-stabilized rsv F single-chain 9-24 ds- CAV1 variant. | x-ray diffraction | F | — | — |
| 5K6H | Crystal structure of prefusion-stabilized rsv F single-chain 9-10 ds- CAV1 A149C-Y458C variant. | x-ray diffraction | F | — | — |
| 5K6I | Crystal structure of prefusion-stabilized RSV F single-chain 9-10 DS-Cav1 A149C-Y458C… | x-ray diffraction | F | ZN, PO4, NAG | 4 (best 0.52) |
| 5K6I | Crystal structure of prefusion-stabilized rsv F single-chain 9-10 ds- CAV1 A149C-Y458C… | x-ray diffraction | F | ZN, PO4, NAG | — |
| 5TOJ | Crystal structure of the rsv F glycoprotein in complex with the neutralizing single-domain antibody… | x-ray diffraction | A, B, C | NAG | — |
| 5TOK | Crystal structure of the rsv F glycoprotein in complex with the neutralizing single-domain antibody… | x-ray diffraction | A, B, C | NAG, PO4 | — |
| 5TPN | Crystal structure of rsv F in complex with human antibody HRSV90 | x-ray diffraction | A | — | — |
| 5U68 | Structural basis for antibody cross-neutralization of respiratory syncytial virus and human… | x-ray diffraction | A, B, C | — | — |
| 5UDC | Crystal structure of rsv F A2 bound to MEDI8897 | x-ray diffraction | F, A, D | NAG, CL | — |
| 5W23 | Crystal structure of rsv F in complex with 5C4 Fab | x-ray diffraction | A, B, C | ZN | — |
| 6CXC | 3.9A cryo-EM structure of murine antibody bound at a novel epitope of respiratory syncytial virus… | electron microscopy | A, B, C, D, E, F | NAG | — |
| 6DC3 | Rsv prefusion F bound to RSD5 Fab | x-ray diffraction | F | NAG, SO4 | — |
| 6DC5 | Rsv prefusion F in complex with AM22 Fab | x-ray diffraction | A, D, G | NAG, CD | — |
9 records more on the page itself.
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 11 records
- SO4 · Sulfate ion · in 9 records
- PO4 · Phosphate ion · in 3 records
- ZN · Zinc ion · in 3 records
- 336 · 4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide · in 1 record
- 5NK · 2-[[2-[[1-(2-azanylethyl)piperidin-4-yl]amino]-4-methyl-benzimidazol-1-yl]methyl]-6-methyl-pyridin-3-ol · in 1 record
- 5NM · 3-[[5-bromanyl-1-(3-methylsulfonylpropyl)benzimidazol-2-yl]methyl]-1-cyclopropyl-imidazo[4,5-c]pyridin-2-one · in 1 record
- 5NP · (9~{b}~{R})-9~{b}-(4-chlorophenyl)-1-pyridin-3-ylcarbonyl-2,3-dihydroimidazo[5,6]pyrrolo[1,2-~{a}]pyridin-5-one · in 1 record
- CD · Cadmium ion · in 1 record
- CL · Chloride ion · in 1 record
- TM3 · 2-[[6-[[[2-(3-hydroxypropyl)-5-methylphenyl]amino]methyl]-2-[[3-(4-morpholinyl)propyl]amino]-1H-benzimidazol-1-yl]methyl]-6-methyl-3-pyridinol · in 1 record
Elsewhere
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