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MolNFT v1 · #123979 · protein

Crystal structure of the UAF1/WDR20/USP12 complex

5K1C: “Crystal structure of the UAF1/WDR20/USP12 complex”. X-ray diffraction, 3 ligands (TAM, ZN, PO4). MolNFT v1 #123979 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5K1C
Type
protein
Length
1,224 residues
Chains
3
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
O75317, Q8TAF3, Q8TBZ3
Ligands
TAM, ZN, PO4

Structure

x-ray diffraction · 3 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein302—O75317
B—protein515—Q8TAF3
C—protein407—Q8TBZ3

Ligands and binding sites

  • TAM · Tris(hydroxyethyl)aminomethane · ligand · chains C
  • ZN · Zinc ion · metal · chains A
  • PO4 · Phosphate ion · ion · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 5K1C · Crystal structure of the UAF1/WDR20/USP12 complex · the same entry in another collection · chain A against A, TM-score 1.00
  • Q8TAF3 · AlphaFold monomer V2.0 prediction for wd repeat-containing protein 48 (Q8TAF3) · a predicted model of the same protein · chain B against A, TM-score 0.99
  • Q8TBZ3 · AlphaFold monomer V2.0 prediction for wd repeat-containing protein 20 (Q8TBZ3) · a predicted model of the same protein · chain C against A, TM-score 0.97
  • O75317 · AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 12 (O75317) · a predicted model of the same protein · chain A against A, TM-score 0.93

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