MolNFT v1 · #123913 · protein
Helical filament
5JZC · DNA repair protein RAD51 homolog 1: “Helical filament”. Electron microscopy, 20 pockets (best druggability 0.88). MolNFT v1 #123913 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5JZC
- Type
- protein
- Length
- 2,184 residues
- Chains
- 7
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA repair protein RAD51 homolog 1
- UniProt
- Q06609
- Pockets
- 20 · best druggability 0.88
Structure
electron microscopy · 1 distinct chain · 37% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G | DNA repair protein RAD51 homolog 1 | protein | 312 | 37% helix, 13% strand | Q06609 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1121 | 0.88 | 0.90 | 179 | empty |
| 2 | 885 | 0.88 | 0.90 | 152 | empty |
| 3 | 681 | 0.86 | 0.90 | 123 | empty |
| 4 | 343 | 0.81 | 0.90 | 74 | empty |
| 5 | 353 | 0.80 | 0.90 | 58 | empty |
Interfaces
6 interfaces between chains.
- B–C · 1187 Ų buried · 7 hydrogen bonds · protein-protein
- A–B · 1182 Ų buried · 7 hydrogen bonds · protein-protein
- D–E · 1178 Ų buried · 6 hydrogen bonds · protein-protein
- E–F · 1176 Ų buried · 6 hydrogen bonds · protein-protein
- C–D · 1173 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q06609
- Elsewhere: RCSB PDB 5JZC · PDBe 5JZC · UniProt Q06609
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