UniProt Q06609
DNA repair protein RAD51 homolog 1 (Q06609)
DNA repair protein RAD51 homolog 1 (UniProt Q06609): 32 experimental structures on GenesisL1, 7 ligands bound, 256 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q06609
- Protein
- DNA repair protein RAD51 homolog 1
- Experimental structures
- 32
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 256 · 18 records with a druggable one
Structures
32 records of Q06609 in the MolNFT archive: 32 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1B22 | RAD51 (N-terminal domain) | solution nmr | A | — | — |
| 1B22 | RAD51 (N-terminal domain) | solution nmr | A | — | — |
| 1N0W | Crystal structure of a RAD51-BRCA2 BRC repeat complex | x-ray diffraction | A | — | — |
| 1N0W | Crystal structure of a RAD51-BRCA2 brc repeat complex | x-ray diffraction | A | — | — |
| 5H1B | Human RAD51 presynaptic complex | electron microscopy | A, B, C | ANP, MG | 18 (best 0.78) |
| 5H1B | Human RAD51 presynaptic complex | electron microscopy | A, B, C | — | — |
| 5H1C | Human RAD51 post-synaptic complexes | electron microscopy | A, B, C | MG, ANP | 19 (best 0.77) |
| 5H1C | Human RAD51 post-synaptic complexes | electron microscopy | A, B, C | — | — |
| 5JZC | helical filament | electron microscopy | A, B, C, D, E, F, G | — | 20 (best 0.88) |
| 5JZC | Helical filament | electron microscopy | A, B, C, D, E, F, G | — | — |
| 5NP7 | CryoEM structure of Human Rad51 on single-stranded DNA to 4.2A resolution. | electron microscopy | A, B, C, D, E, F, G | ANP | 20 (best 0.79) |
| 5NP7 | Cryoem structure of human RAD51 on single-stranded DNA to 4.2A resolution. | electron microscopy | A, B, C, D, E, F, G | ANP | — |
| 5NWL | Crystal structure of a human RAD51-ATP filament. | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | MG, ATP | 20 (best 0.85) |
| 5NWL | Crystal structure of a human RAD51-ATP filament. | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | MG, ATP | — |
| 7C9A | Human RAD51 post-synaptic complexes mutant (V273P, D274G) | electron microscopy | A, B, C | CA, ANP | — |
| 7C9A | Human RAD51 post-synaptic complexes mutant (V273P, D274G) | electron microscopy | A, B, C | CA, ANP | — |
| 7EJC | Human RAD51 presynaptic complex | electron microscopy | A, C, B | MG, J46, ANP | — |
| 7EJE | Human RAD51 post-synaptic complex | electron microscopy | A, B, C | MG, ANP | — |
| 8BR2 | CryoEM structure of the post-synaptic RAD51 nucleoprotein filament in the presence of ATP and Ca2+ | electron microscopy | A, B, C, D, E, F | CA, ATP | 20 (best 0.82) |
| 8GYK | CryoEM structure of the RAD51_ADP filament | electron microscopy | A, B, C, D, E, F, G, H | ADP, MG | 20 (best 0.83) |
| 8JND | The cryo-EM structure of the nonameric RAD51 ring bound to the nucleosome with the linker DNA… | electron microscopy | K, L, M, N, O, P, Q, R, S | — | 14 (best 0.79) |
| 8JNF | The cryo-EM structure of the RAD51 filament bound to the nucleosome | electron microscopy | K, L, M, N, O, P | — | 8 (best 0.85) |
| 8PBC | RAD51 filament on ssDNA bound by the BRCA2 c-terminus | electron microscopy | A, B, C, D, E, F, G, H, I, J, K | ATP, CA | 20 (best 0.82) |
| 8PBD | RAD51 filament on dsDNA bound by the BRCA2 c-terminus | electron microscopy | A, B, C, D, E, F, G, H, I, J | ATP, CA | 20 (best 0.82) |
| 8R64 | Cryo-EM structure of the FIGNL1 AAA hexamer bound to RAD51 | electron microscopy | G | — | 1 (best 0.81) |
| 8RCD | RAD51 nucleoprotein filament on abasic single-stranded DNA | electron microscopy | A, B, C, D, E, F, G, H | ATP, CA | 20 (best 0.82) |
| 8RCF | RAD51 nucleoprotein filament on double-stranded abasic DNA | electron microscopy | A, B, C, D, E, F, G, H | CA, ATP | 20 (best 0.80) |
| 8UVW | Crystal structure of RAD51-BRCA2 Cter complex | x-ray diffraction | B, D | ADP, BEF | 5 (best 0.78) |
| 8XBV | The cryo-EM structure of the RAD51 L1 and L2 loops bound to the linker DNA with the sticky end of… | electron microscopy | K, L | — | 3 (best 0.74) |
| 8XBX | The cryo-EM structure of the RAD51 L2 loop bound to the linker DNA with the blunt end of the… | electron microscopy | K, L, M | — | 4 (best 0.76) |
| 8XBY | The cryo-EM structure of the RAD51 L1 and L2 loops bound to the linker DNA with the blunt end of… | electron microscopy | K, L, M | — | 4 (best 0.77) |
| Q06609 | AlphaFold monomer V2.0 prediction for DNA repair protein RAD51 homolog 1 (Q06609) | — | — | — |
Ligands
- ANP · Phosphoaminophosphonic acid-adenylate ester · in 8 records
- ATP · Adenosine-5'-triphosphate · in 7 records
- CA · Calcium ion · in 7 records
- MG · Magnesium ion · in 7 records
- ADP · Adenosine-5'-diphosphate · in 2 records
- BEF · Beryllium trifluoride ion · in 1 record
- J46 · 4-bromanyl-N-(4-bromophenyl)-3-[(phenylmethyl) sulfamoyl]benzamide · in 1 record
Elsewhere
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