MolNFT v1 · #123853 · protein
Crystal structure of murine TNFAIP8 C165S mutant
5JXD · Tumor necrosis factor alpha-induced protein 8: “Crystal structure of murine TNFAIP8 C165S mutant”. X-ray diffraction, 1 ligand (6OU), 2 pockets (best druggability 0.83). MolNFT v1 #123853 on GenesisL1: 3D structure, binding sites…
- PDB
- 5JXD
- Type
- protein
- Length
- 186 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tumor necrosis factor alpha-induced protein 8
- UniProt
- Q921Z5
- Ligands
- 6OU
- Pockets
- 2 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 77% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tumor necrosis factor alpha-induced protein 8 | protein | 186 | 77% helix, 0% strand | Q921Z5 |
Ligands and binding sites
- 6OU · [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 563 | 0.83 | 0.88 | 45 | 6OU |
| 2 | 60 | 0.34 | 0.77 | 14 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q921Z5
- Elsewhere: RCSB PDB 5JXD · PDBe 5JXD · UniProt Q921Z5
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