MolNFT v1 · #123847 · protein

Cysteine mutant (C224A) structure of as (III) S-adenosyl methyltransferase

5JX7 · Arsenic methyltransferase: “Cysteine mutant (C224A) structure of as (III) S-adenosyl methyltransferase”. X-ray diffraction, 1 ligand (CA), 3 pockets (best druggability 0.59). MolNFT v1 #123847 on GenesisL1: 3D structure, binding…

PDB: 5JX7
Type: protein
Length: 323 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Arsenic methyltransferase
UniProt: C0JV69
Ligands: CA
Pockets: 3 · best druggability 0.59

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Arsenic methyltransferase	protein	323	33% helix, 23% strand	C0JV69

Ligands and binding sites

CA · Calcium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	180	0.59	0.82	24	CA
2	88	0.46	0.81	14	empty
3	119	0.39	0.75	28	empty

Compared structures

5JX7 · Cysteine mutant (C224A) structure of As (III) S-adenosyl methyltransferase · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C0JV69
Elsewhere: RCSB PDB 5JX7 · PDBe 5JX7 · UniProt C0JV69

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