MolNFT v1 · #123695 · protein

Structural model of a apo G-protein alpha subunit determined with NMR residual dipolar couplings and saxs

5JS7 · Guanine nucleotide-binding protein G(I) subunit alpha-1: “Structural model of a apo G-protein alpha subunit determined with NMR residual dipolar couplings and saxs”. Solution nmr, 3 pockets (best druggability 0.66). MolNFT v1…

PDB: 5JS7
Type: protein
Length: 323 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Guanine nucleotide-binding protein G(I) subunit alpha-1
UniProt: P63096
Pockets: 3 · best druggability 0.66

Structure

solution nmr · 1 distinct chain · 50% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Guanine nucleotide-binding protein G(I) subunit alpha-1	protein	323	50% helix, 12% strand	P63096

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	589	0.66	0.76	75	empty
2	115	0.42	0.77	20	empty
3	59	0.34	0.78	18	empty

Compared structures

5JS7 · Structural model of a apo G-protein alpha subunit determined with NMR residual dipolar… · the same entry in another collection · chain A against A, TM-score 1.00
P63096 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I) subunit… · a predicted model of the same protein · chain A against A, TM-score 0.69

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P63096
Elsewhere: RCSB PDB 5JS7 · PDBe 5JS7 · UniProt P63096

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.