MolNFT v1 · #123412 · protein

Crystal structure of the central domain of human AKAP18 GAMMA/DELTA in complex with malonate

5JJ2 · A-kinase anchor protein 7 isoform gamma: “Crystal structure of the central domain of human AKAP18 GAMMA/DELTA in complex with malonate”. X-ray diffraction, 1 pocket (best druggability 0.58). MolNFT v1 #123412 on GenesisL1: 3D…

PDB: 5JJ2
Type: protein
Length: 211 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: A-kinase anchor protein 7 isoform gamma
UniProt: Q9P0M2
Pockets: 1 · best druggability 0.58

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	A-kinase anchor protein 7 isoform gamma	protein	211	39% helix, 27% strand	Q9P0M2

Ligands and binding sites

MLI · Malonate ion · additive · 6 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	264	0.58	0.78	33	MLI

Compared structures

5JJ2 · Crystal structure of the central domain of human AKAP18 gamma/delta in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Q9P0M2 · AlphaFold monomer V2.0 prediction for a-kinase anchor protein 7 isoform gamma (Q9P0M2) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9P0M2
Elsewhere: RCSB PDB 5JJ2 · PDBe 5JJ2 · UniProt Q9P0M2

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