MolNFT v1 · #123384 · protein
Crystal structure of the BRD9 bromodomain and hit 1
5JI8 · Bromodomain-containing protein 9: “Crystal structure of the BRD9 bromodomain and hit 1”. X-ray diffraction, 1 ligand (6KT), 1 pocket (best druggability 0.45). MolNFT v1 #123384 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 5JI8
- Type
- protein
- Length
- 100 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Bromodomain-containing protein 9
- UniProt
- Q9H8M2
- Ligands
- 6KT
- Pockets
- 1 · best druggability 0.45
Structure
x-ray diffraction · 1 distinct chain · 62% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Bromodomain-containing protein 9 | protein | 100 | 62% helix, 0% strand | Q9H8M2 |
Ligands and binding sites
- 6KT · 2-amino-1,3-benzothiazole-6-carboxamide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 76 | 0.45 | 0.81 | 18 | 6KT |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H8M2
- Elsewhere: RCSB PDB 5JI8 · PDBe 5JI8 · UniProt Q9H8M2
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