MolNFT v1 · #123220 · protein
Crystal structure of I9-I11 tandem from titin (P1)
5JDE: “Crystal structure of I9-I11 tandem from titin (P1)”. X-ray diffraction, 2 pockets (best druggability 0.62). MolNFT v1 #123220 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5JDE
- Type
- protein
- Length
- 519 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Titin
- EC
- 2.7.11.1
- UniProt
- Q8WZ42
- Pockets
- 2 · best druggability 0.62
Structure
x-ray diffraction · 2 distinct chains · 3% helix, 55% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Titin (EC 2.7.11.1) | protein | 260 | 3% helix, 55% strand | Q8WZ42 |
| B | Titin (EC 2.7.11.1) | protein | 259 | 3% helix, 56% strand | Q8WZ42 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 542 | 0.62 | 0.75 | 57 | empty |
| 2 | 87 | 0.38 | 0.76 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 176 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 5JDE · Crystal structure of I9-I11 tandem from titin (P1) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8WZ42
- Elsewhere: RCSB PDB 5JDE · PDBe 5JDE · UniProt Q8WZ42
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