UniProt Q8WZ42
Titin (Q8WZ42)
Titin (UniProt Q8WZ42), EC 2.7.11.1: 75 experimental structures on GenesisL1, 5 ligands bound, 22 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q8WZ42
- Protein
- Titin
- EC
- 2.7.11.1
- Experimental structures
- 75
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 22 · 1 record with a druggable one
Structures
75 records of Q8WZ42 in the MolNFT archive: 75 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1TNM | Tertiary structure of an immunoglobulin-like domain from the giant muscle protein titin: a new… | solution nmr | A | — | — |
| 1TNM | Tertiary structure of an immunoglobulin-like domain from the giant muscle protein titin: a new… | solution nmr | A | — | — |
| 1TNN | Tertiary structure of an immunoglobulin-like domain from the giant muscle protein titin: a new… | solution nmr | A | — | — |
| 1TNN | Tertiary structure of an immunoglobulin-like domain from the giant muscle protein titin: a new… | solution nmr | A | — | — |
| 1WAA | IG27 protein domain | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1WAA | IG27 protein domain | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2A38 | Crystal structure of the N-Terminus of titin | x-ray diffraction | A, B, C | — | — |
| 2A38 | Crystal structure of the N-terminus of titin | x-ray diffraction | A, B, C | — | — |
| 2BK8 | M1 domain from titin | x-ray diffraction | A | — | — |
| 2BK8 | M1 domain from titin | x-ray diffraction | A | — | — |
| 2F8V | Structure of full length telethonin in complex with the N-terminus of titin | x-ray diffraction | A, B, C, D | — | — |
| 2F8V | Structure of full length telethonin in complex with the N-terminus of titin | x-ray diffraction | A, B, C, D | — | — |
| 2ILL | Anomalous substructure of Titin-A168169 | x-ray diffraction | A | — | — |
| 2ILL | Anomalous substructure of titin-A168169 | x-ray diffraction | A | — | — |
| 2J8H | Structure of the immunoglobulin tandem repeat A168-A169 of titin | x-ray diffraction | A | — | — |
| 2J8H | Structure of the immunoglobulin tandem repeat A168-A169 of titin | x-ray diffraction | A | — | — |
| 2J8O | Structure of the immunoglobulin tandem repeat of titin A168-A169 | x-ray diffraction | A, B | — | — |
| 2J8O | Structure of the immunoglobulin tandem repeat of titin A168-A169 | x-ray diffraction | A, B | — | — |
| 2NZI | Crystal structure of domains A168-A170 from titin | x-ray diffraction | A, B | — | — |
| 2NZI | Crystal structure of domains A168-A170 from titin | x-ray diffraction | A, B | — | — |
| 2RQ8 | Solution NMR structure of titin I27 domain mutant | solution nmr | A | — | — |
| 2RQ8 | Solution NMR structure of titin I27 domain mutant | solution nmr | A | — | — |
| 2WP3 | Crystal structure of the Titin M10-Obscurin like 1 Ig complex | x-ray diffraction | T | — | — |
| 2WP3 | Crystal structure of the titin M10-obscurin like 1 ig complex | x-ray diffraction | T | — | — |
| 2WWK | Crystal structure of the Titin M10-Obscurin like 1 Ig F17R mutant complex | x-ray diffraction | T | — | — |
| 2WWK | Crystal structure of the titin M10-obscurin like 1 ig F17R mutant complex | x-ray diffraction | T | — | — |
| 2WWM | Crystal structure of the Titin M10-Obscurin like 1 Ig complex in space group P1 | x-ray diffraction | D, T | — | — |
| 2WWM | Crystal structure of the titin M10-obscurin like 1 ig complex in space group P1 | x-ray diffraction | D, T | — | — |
| 2Y9R | Crystal structure of the M10 domain of Titin | x-ray diffraction | T | — | — |
| 2Y9R | Crystal structure of the M10 domain of titin | x-ray diffraction | T | — | — |
| 3KNB | Crystal structure of the titin C-terminus in complex with obscurin-like 1 | x-ray diffraction | A | — | — |
| 3KNB | Crystal structure of the titin C-terminus in complex with obscurin- like 1 | x-ray diffraction | A | — | — |
| 3LCY | Titin Ig tandem domains A164-A165 | x-ray diffraction | A, B, C, D | — | — |
| 3LCY | Titin ig tandem domains A164-A165 | x-ray diffraction | A, B, C, D | — | — |
| 3LPW | Crystal structure of the FnIII-tandem A77-A78 from the A-band of titin | x-ray diffraction | A, B | — | — |
| 3LPW | Crystal structure of the fniii-tandem A77-A78 from the a-band of titin | x-ray diffraction | A, B | — | — |
| 3PUC | Atomic resolution structure of titin domain M7 | x-ray diffraction | A | — | — |
| 3PUC | Atomic resolution structure of titin domain M7 | x-ray diffraction | A | — | — |
| 3Q5O | Crystal structure of human titin domain M10 | x-ray diffraction | A, B | — | — |
| 3Q5O | Crystal structure of human titin domain M10 | x-ray diffraction | A, B | — | — |
| 3QP3 | Crystal structure of titin domain M4, tetragonal form | x-ray diffraction | A, B, C | — | — |
| 3QP3 | Crystal structure of titin domain M4, tetragonal form | x-ray diffraction | A, B, C | — | — |
| 4C4K | Crystal structure of the titin M10-Obscurin Ig domain 1 complex | x-ray diffraction | T | — | — |
| 4C4K | Crystal structure of the titin M10-obscurin ig domain 1 complex | x-ray diffraction | T | — | — |
| 4JNW | Bacterially expressed Titin Kinase | x-ray diffraction | A, B | — | — |
| 4JNW | Bacterially expressed titin kinase | x-ray diffraction | A, B | — | — |
| 4O00 | Crystal structure of the Titin A-band domain A3 | x-ray diffraction | A, B | — | — |
| 4O00 | Crystal structure of the titin a-band domain A3 | x-ray diffraction | A, B | — | — |
| 4QEG | Crystal structure of domain I10 from titin (space group P41) | x-ray diffraction | A | — | — |
| 4QEG | Crystal structure of domain I10 from titin (space group P41) | x-ray diffraction | A | — | — |
| 4UOW | Crystal structure of the titin M10-Obscurin Ig domain 1 complex | x-ray diffraction | 0, 2, 4, 6, 8, A, C, E, G, I, K, M, O, Q, S, U, W, Y | — | — |
| 4UOW | Crystal structure of the titin M10-obscurin ig domain 1 complex | x-ray diffraction | 0, 2, 4, 6, 8, A, C, E, G, I, K, M, O, Q, S, U, W, Y | — | — |
| 5BS0 | Mage-A3 reactive TCR in complex with titin epitope in HLA-A1 | x-ray diffraction | C | — | — |
| 5JDD | Crystal structure of I9-I11 tandem from titin (P212121) | x-ray diffraction | A | — | — |
| 5JDD | Crystal structure of I9-I11 tandem from titin (P212121) | x-ray diffraction | A | — | — |
| 5JDE | Crystal structure of I9-I11 tandem from titin (P1) | x-ray diffraction | A, B | — | — |
| 5JDE | Crystal structure of I9-I11 tandem from titin (P1) | x-ray diffraction | A, B | — | — |
| 5JDJ | Crystal structure of domain I10 from titin in space group P212121 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | CA | 17 (best 0.87) |
| 5JDJ | Crystal structure of domain I10 from titin in space group P212121 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | — | — |
| 5JOE | Crystal structure of I81 from titin | x-ray diffraction | A | — | — |
15 records more on the page itself.
Ligands
Experiment against prediction
- 6SDB chain B against the predicted model P07585: TM-score 0.29, RMSD 5.91 Å
- 6SDB chain A against the predicted model P07585: TM-score 0.26, RMSD 5.98 Å
- 6SDB chain C against the predicted model P07585: TM-score 0.26, RMSD 5.08 Å
- 6SDB chain D against the predicted model P07585: TM-score 0.25, RMSD 4.36 Å
- 6SDB chain E against the predicted model P07585: TM-score 0.25, RMSD 6.15 Å
Elsewhere
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