MolNFT v1 · #123207 · protein
Crystal structure of ARAP3 rhogap domain
5JD0 · Arf-gap with rho-gap domain, ank repeat and pH domain…: “Crystal structure of ARAP3 rhogap domain”. X-ray diffraction, 3 pockets (best druggability 0.67). MolNFT v1 #123207 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5JD0
- Type
- protein
- Length
- 402 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Arf-gap with rho-gap domain, ank repeat and pH domain- containing protein 3
- UniProt
- Q8WWN8
- Pockets
- 3 · best druggability 0.67
Structure
x-ray diffraction · 2 distinct chains · 66% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Arf-gap with rho-gap domain, ank repeat and pH domain- containing protein 3 | protein | 201 | 67% helix, 1% strand | Q8WWN8 |
| B | Arf-gap with rho-gap domain, ank repeat and pH domain- containing protein 3 | protein | 201 | 65% helix, 2% strand | Q8WWN8 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 385 | 0.67 | 0.81 | 42 | empty |
| 2 | 114 | 0.35 | 0.73 | 20 | empty |
| 3 | 53 | 0.25 | 0.73 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 552 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8WWN8
- Elsewhere: RCSB PDB 5JD0 · PDBe 5JD0 · UniProt Q8WWN8
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