MolNFT v1 · #12317 · protein

Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II

1KD6: “Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II”. Solution nmr, 3 pockets (best druggability 0.71). MolNFT v1 #12317 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1KD6
Type: protein
Length: 179 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Equinatoxin II
UniProt: P61914
Pockets: 3 · best druggability 0.71

Structure

solution nmr · 1 distinct chain · 7% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Equinatoxin II	protein	179	7% helix, 36% strand	P61914

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	59	0.71	0.97	20	empty
2	192	0.61	0.82	37	empty
3	189	0.47	0.75	29	empty

Compared structures

1KD6 · Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II · the same entry in another collection · chain A against A, TM-score 1.00
P61914 · AlphaFold monomer V2.0 prediction for delta-actitoxin-AEQ1A (P61914) · a predicted model of the same protein · chain A against A, TM-score 0.83

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P61914
Elsewhere: RCSB PDB 1KD6 · PDBe 1KD6 · UniProt P61914

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