MolNFT v1 · #122938 · protein

Apo-structure of humanised rada-mutant HUMRADA22F

5J4L · DNA repair and recombination protein rada: “Apo-structure of humanised rada-mutant HUMRADA22F”. X-ray diffraction, 1 ligand (CL), 2 pockets (best druggability 0.64). MolNFT v1 #122938 on GenesisL1: 3D structure, binding sites and…

PDB: 5J4L
Type: protein
Length: 226 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA repair and recombination protein rada
UniProt: O74036
Ligands: CL
Pockets: 2 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA repair and recombination protein rada	protein	226	38% helix, 26% strand	O74036

Ligands and binding sites

CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	162	0.64	0.85	27	empty
2	52	0.30	0.76	18	CL

Compared structures

5J4L · Apo-structure of humanised RadA-mutant humRadA22F · the same entry in another collection · chain A against A, TM-score 1.00
O74036 · AlphaFold monomer V2.0 prediction for DNA repair and recombination protein rada (O74036) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O74036
Elsewhere: RCSB PDB 5J4L · PDBe 5J4L · UniProt O74036

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