MolNFT v1 · #122843 · protein

Lassa virus L protein cap-snatching endonuclease. bound to one manganese ion

5J1N · RNA-directed RNA polymerase L: “Lassa virus L protein cap-snatching endonuclease. bound to one manganese ion”. X-ray diffraction, 1 ligand (MN3), 1 pocket (best druggability 0.40). MolNFT v1 #122843 on GenesisL1: 3D structure…

PDB: 5J1N
Type: protein
Length: 171 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA-directed RNA polymerase L
EC: 2.7.7.48
UniProt: Q6GWS6
Ligands: MN3
Pockets: 1 · best druggability 0.40

Structure

x-ray diffraction · 1 distinct chain · 53% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA-directed RNA polymerase L (EC 2.7.7.48)	protein	171	53% helix, 15% strand	Q6GWS6

Ligands and binding sites

MN3 · Manganese (III) ion · metal · chains A
MPD · (4S)-2-methyl-2,4-pentanediol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	150	0.40	0.73	27	MN3

Compared structures

5J1N · Lassa virus L protein cap-snatching endonuclease. Bound to one manganese ion · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6GWS6
Elsewhere: RCSB PDB 5J1N · PDBe 5J1N · UniProt Q6GWS6

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