MolNFT v1 · #122703 · protein
Hcmv DNA polymerase processivity subunit UL44 at neutral pH and low salt
5IXA · DNA polymerase processivity factor: “Hcmv DNA polymerase processivity subunit UL44 at neutral pH and low salt”. X-ray diffraction, 4 pockets (best druggability 0.55). MolNFT v1 #122703 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5IXA
- Type
- protein
- Length
- 501 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA polymerase processivity factor
- UniProt
- P16790
- Pockets
- 4 · best druggability 0.55
Structure
x-ray diffraction · 2 distinct chains · 19% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA polymerase processivity factor | protein | 250 | 19% helix, 44% strand | P16790 |
| B | DNA polymerase processivity factor | protein | 251 | 19% helix, 44% strand | P16790 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 151 | 0.55 | 0.81 | 28 | empty |
| 2 | 149 | 0.52 | 0.80 | 29 | empty |
| 3 | 100 | 0.36 | 0.74 | 21 | empty |
| 4 | 62 | 0.28 | 0.73 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 827 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 5IXA · HCMV DNA polymerase processivity subunit UL44 at neutral pH and low salt · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16790
- Elsewhere: RCSB PDB 5IXA · PDBe 5IXA · UniProt P16790
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.