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MolNFT v1 · #122690 · protein

Crystal structure of RNA editing factor of designer pls-type PPR/9R protein in complex with MORF9/RIP9

5IWW · Multiple organellar RNA editing factor 9, chloroplastic: “Crystal structure of RNA editing factor of designer pls-type PPR/9R protein in complex with MORF9/RIP9”. X-ray diffraction, 3 pockets (best druggability 0.40). MolNFT v1…

PDB
5IWW
Type
protein
Length
628 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Multiple organellar RNA editing factor 9, chloroplastic; PLS9-ppr
UniProt
Q9LPZ1
Pockets
3 · best druggability 0.40

Structure

x-ray diffraction · 3 distinct chains · 54% helix, 12% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, BMultiple organellar RNA editing factor 9, chloroplasticprotein11027% helix, 30% strandQ9LPZ1
CMultiple organellar RNA editing factor 9, chloroplasticprotein10828% helix, 27% strandQ9LPZ1
DPLS9-pprprotein30074% helix, 0% strand—

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11140.400.7622empty
2790.330.7418empty
3580.250.7214empty

Interfaces

3 interfaces between chains.

  • A–D · 1120 Ų buried · 9 hydrogen bonds · protein-protein
  • C–D · 1069 Ų buried · 9 hydrogen bonds · protein-protein
  • B–D · 1058 Ų buried · 6 hydrogen bonds · protein-protein

Compared structures

  • 5IWW · Crystal structure of RNA editing factor of designer PLS-type PPR/9R protein in complex… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9LPZ1 · AlphaFold monomer V2.0 prediction for multiple organellar RNA editing factor 9… · a predicted model of the same protein · chain A against A, TM-score 0.98

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