MolNFT v1 · #122430 · protein

Structure of transcriptional regulatory repressor protein - ethr from mycobacterium tuberculosis in complex with N-(cyclopentylmethyl) pyrrolidine-1-carboxamide at 1.77A resolution

5IOY · Tetr-family transcriptional regulatory repressor protein: “Structure of transcriptional regulatory repressor protein - ethr from mycobacterium tuberculosis in complex…”. X-ray diffraction, 2 ligands (6C5, SO4), 1 pocket (best…

PDB: 5IOY
Type: protein
Length: 193 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tetr-family transcriptional regulatory repressor protein
UniProt: A5U9I4
Ligands: 6C5, SO4
Pockets: 1 · best druggability 0.80

Structure

x-ray diffraction · 1 distinct chain · 79% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tetr-family transcriptional regulatory repressor protein	protein	193	79% helix, 0% strand	A5U9I4

Ligands and binding sites

6C5 · N-(cyclopentylmethyl)pyrrolidine-1-carboxamide · ligand · 3 copies · chains A
SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	366	0.80	0.89	43	6C5

Compared structures

5IOY · Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A5U9I4
Elsewhere: RCSB PDB 5IOY · PDBe 5IOY · UniProt A5U9I4

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.