MolNFT v1 · #12241 · protein
70KD heat shock cognate protein ATPase domain, K71M mutant
1KAX: “70KD heat shock cognate protein ATPase domain, K71M mutant”. X-ray diffraction, 4 ligands (ATP, K, MG), 1 pocket (best druggability 0.77). MolNFT v1 #12241 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1KAX
- Type
- protein
- Length
- 378 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 70KD heat shock cognate protein
- EC
- 3.6.1.3
- UniProt
- P19120
- Ligands
- ATP, K, MG, CL
- Pockets
- 1 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 70KD heat shock cognate protein (EC 3.6.1.3) | protein | 378 | 40% helix, 29% strand | P19120 |
Ligands and binding sites
- ATP · Adenosine-5'-triphosphate · ligand · chains A
- K · Potassium ion · metal · 3 copies · chains A
- MG · Magnesium ion · metal · chains A
- CL · Chloride ion · ion · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 793 | 0.77 | 0.81 | 75 | MG, K, ATP |
Compared structures
- 1KAX · 70KD heat shock cognate protein ATPase domain, K71M mutant · the same entry in another collection · chain A against A, TM-score 1.00
- P19120 · AlphaFold monomer V2.0 prediction for heat shock cognate 71 kda protein (P19120) · a predicted model of the same protein · chain A against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P19120
- Elsewhere: RCSB PDB 1KAX · PDBe 1KAX · UniProt P19120
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