MolNFT v1 · #122277 · protein
Crystal structure of the kainate receptor GLUK4 ligand binding domain in complex with kainate
5IKB · Glutamate receptor ionotropic, kainate 4,GLUTAMATE receptor…: “Crystal structure of the kainate receptor GLUK4 ligand binding domain in complex with kainate”. X-ray diffraction, 1 ligand (KAI), 1 pocket (best druggability 0.66).…
- PDB
- 5IKB
- Type
- protein
- Length
- 249 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutamate receptor ionotropic, kainate 4,GLUTAMATE receptor ionotropic, kainate 4
- UniProt
- Q01812
- Ligands
- KAI
- Pockets
- 1 · best druggability 0.66
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glutamate receptor ionotropic, kainate 4,GLUTAMATE receptor ionotropic, kainate 4 | protein | 249 | 39% helix, 21% strand | Q01812 |
Ligands and binding sites
- KAI · 3-(carboxymethyl)-4-isopropenylproline · ligand · chains A
- GOL · Glycerol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 170 | 0.66 | 0.86 | 32 | KAI |
Compared structures
- 5IKB · Crystal structure of the kainate receptor GluK4 ligand binding domain in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
- Q01812 · AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, kainate 4 (Q01812) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q01812
- Elsewhere: RCSB PDB 5IKB · PDBe 5IKB · UniProt Q01812
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