Research workbench
Crystal structure of the kainate receptor GLUK4 ligand binding domain in complex with kainate
Analyse Crystal structure of the kainate receptor GLUK4 ligand binding domain in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5IKB
- Type
- protein
- Length
- 249 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutamate receptor ionotropic, kainate 4,GLUTAMATE receptor ionotropic, kainate 4
- UniProt
- Q01812
- Ligands
- KAI
- Pockets
- 1 · best druggability 0.66
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glutamate receptor ionotropic, kainate 4,GLUTAMATE receptor ionotropic, kainate 4 | protein | 249 | 39% helix, 21% strand | Q01812 |
Ligands and binding sites
- KAI · 3-(carboxymethyl)-4-isopropenylproline · ligand · chains A
- GOL · Glycerol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 170 | 0.66 | 0.86 | 32 | KAI |
Compared structures
- 5IKB · Crystal structure of the kainate receptor GluK4 ligand binding domain in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
- Q01812 · AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, kainate 4 (Q01812) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q01812
- Elsewhere: RCSB PDB 5IKB · PDBe 5IKB · UniProt Q01812
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