MolNFT v1 · #121999 · protein

Structure of UTP6

5IC8 · Putative uncharacterized protein: “Structure of UTP6”. X-ray diffraction, 16 pockets (best druggability 0.77). MolNFT v1 #121999 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5IC8
Type: protein
Length: 1,077 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative uncharacterized protein
UniProt: G0S387
Pockets: 16 · best druggability 0.77

Structure

x-ray diffraction · 4 distinct chains · 71% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative uncharacterized protein	protein	284	69% helix, 1% strand	G0S387
B	Putative uncharacterized protein	protein	282	70% helix, 1% strand	G0S387
C	Putative uncharacterized protein	protein	252	74% helix, 0% strand	G0S387
D	Putative uncharacterized protein	protein	259	72% helix, 0% strand	G0S387

Pockets

16 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	879	0.77	0.80	67	empty
2	366	0.57	0.75	30	empty
3	376	0.53	0.73	40	empty
4	74	0.51	0.85	23	empty
5	158	0.51	0.78	26	empty

Interfaces

4 interfaces between chains.

B–C · 691 Å² buried · 8 hydrogen bonds · protein-protein
A–B · 560 Å² buried · 9 hydrogen bonds · protein-protein
A–C · 76 Å² buried · 0 hydrogen bonds · protein-protein
B–D · 10 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

5IC8 · Structure of UTP6 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G0S387
Elsewhere: RCSB PDB 5IC8 · PDBe 5IC8 · UniProt G0S387

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