Research workbench
Structure of UTP6
Analyse Structure of UTP6 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5IC8
- Type
- protein
- Length
- 1,077 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative uncharacterized protein
- UniProt
- G0S387
- Pockets
- 16 · best druggability 0.77
Structure
x-ray diffraction · 4 distinct chains · 71% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative uncharacterized protein | protein | 284 | 69% helix, 1% strand | G0S387 |
| B | Putative uncharacterized protein | protein | 282 | 70% helix, 1% strand | G0S387 |
| C | Putative uncharacterized protein | protein | 252 | 74% helix, 0% strand | G0S387 |
| D | Putative uncharacterized protein | protein | 259 | 72% helix, 0% strand | G0S387 |
Pockets
16 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 879 | 0.77 | 0.80 | 67 | empty |
| 2 | 366 | 0.57 | 0.75 | 30 | empty |
| 3 | 376 | 0.53 | 0.73 | 40 | empty |
| 4 | 74 | 0.51 | 0.85 | 23 | empty |
| 5 | 158 | 0.51 | 0.78 | 26 | empty |
Interfaces
4 interfaces between chains.
- B–C · 691 Ų buried · 8 hydrogen bonds · protein-protein
- A–B · 560 Ų buried · 9 hydrogen bonds · protein-protein
- A–C · 76 Ų buried · 0 hydrogen bonds · protein-protein
- B–D · 10 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 5IC8 · Structure of UTP6 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G0S387
- Elsewhere: RCSB PDB 5IC8 · PDBe 5IC8 · UniProt G0S387
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