MolNFT v1 · #121805 · protein

Alcohol oxidase from pichia pastoris

5I68 · Alcohol oxidase 1: “Alcohol oxidase from pichia pastoris”. Electron microscopy, 2 ligands (FAD, MG), 9 pockets (best druggability 0.85). MolNFT v1 #121805 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5I68
Type: protein
Length: 662 residues
Chains: 1
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Alcohol oxidase 1
EC: 1.1.3.13
UniProt: F2QY27
Ligands: FAD, MG
Pockets: 9 · best druggability 0.85

Structure

electron microscopy · 1 distinct chain · 27% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Alcohol oxidase 1 (EC 1.1.3.13)	protein	662	27% helix, 18% strand	F2QY27

Ligands and binding sites

FAD · Flavin-adenine dinucleotide · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	546	0.85	0.90	60	MG, FAD
2	518	0.65	0.76	51	empty
3	222	0.56	0.79	24	empty
4	205	0.50	0.76	30	empty
5	212	0.48	0.75	28	empty

Compared structures

5I68 · Alcohol oxidase from Pichia pastoris · the same entry in another collection · chain A against A, TM-score 1.00
F2QY27 · AlphaFold monomer V2.0 prediction for alcohol oxidase 1 (F2QY27) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt F2QY27
Elsewhere: RCSB PDB 5I68 · PDBe 5I68 · UniProt F2QY27

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