GL1X · GenesisL1 explorer

MolNFT v1 · #121797 · protein

CDK8-cycc in complex with 8-(1-methyl-2,2-dioxo-2,3-dihydro-1H-2L6- BENZO[C]ISOTHIAZOL-5-yl)-[1,6]NAPHTHYRIDINE-2-carboxylic acid methylamide

5I5Z: “CDK8-cycc in complex with 8-(1-methyl-2,2-dioxo-2,3-dihydro-1H-2L6…”. X-ray diffraction. MolNFT v1 #121797 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5I5Z
Type
protein
Length
611 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P49336, P24863

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein345—P49336
B—protein266—P24863

Compared structures

  • 5I5Z · CDK8-CYCC IN COMPLEX WITH 8-(1-Methyl-2,2-dioxo-2,3-dihydro-1H-2l6-benzo[c]isothiazol-5-yl… · the same entry in another collection · chain A against A, TM-score 1.00
  • P24863 · AlphaFold monomer V2.0 prediction for cyclin-C (P24863) · a predicted model of the same protein · chain B against A, TM-score 0.99
  • P49336 · AlphaFold monomer V2.0 prediction for cyclin-dependent kinase 8 (P49336) · a predicted model of the same protein · chain A against A, TM-score 0.97

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