MolNFT v1 · #121746 · protein

Crystal structure of transketolase from pichia stipitis

5I4I: “Crystal structure of transketolase from pichia stipitis”. X-ray diffraction, 4 pockets (best druggability 0.55). MolNFT v1 #121746 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5I4I
Type: protein
Length: 676 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transketolase
EC: 2.2.1.1
UniProt: P34736
Pockets: 4 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transketolase (EC 2.2.1.1)	protein	676	45% helix, 13% strand	P34736

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	258	0.55	0.77	36	empty
2	66	0.50	0.85	18	empty
3	111	0.38	0.74	16	empty
4	56	0.28	0.74	14	empty

Compared structures

5I4I · Crystal Structure of Transketolase from Pichia Stipitis · the same entry in another collection · chain A against A, TM-score 1.00
P34736 · AlphaFold monomer V2.0 prediction for transketolase (P34736) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P34736
Elsewhere: RCSB PDB 5I4I · PDBe 5I4I · UniProt P34736

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